HGF and non-small cell lung carcinoma: In the latter case, we took advantage of the known role of HGF/Met signaling in inducing EMT [10] and compared EMT transcription factor (TF) expression in human non-small cell lung cancer (NSCLC) H596 tumors grown in severe combined immunodeficiency (SCID) mice to those implanted in SCID mice containing a homozygous human HGF (hHGF) knock-in mutation.