Some of these molecules such as EGFR, PTPN6, LCK, CSF2RB, IL2RG, MYC, FOS, CXCR4, PTPRC and TNFRSF14 are well studied in RA by other workers and are reported to play a role in the pathogenesis of RA. This evidence concerns the gene PTPN6 and rheumatoid arthritis.