CKS1B has been used the most widely to detect 1q21 gain and when it is ectopically overexpressed, promotes proliferation and prevents apoptosis of MM cells via p27‐dependent and independent processes.45 However, CKS1B amplification or overexpression by itself might not correlate to short survival of MM patients.46 It is also noteworthy that CKS1B expression has been determined exclusively at mRNA level so far,47 which does not necessarily reflect its protein level and function. This evidence concerns the gene CKS1B and Miyoshi myopathy.