Furthermore, DUXAP8 is positively related to MAGEA4, GABRA3 expression, and negatively related to INPP5A, TIMP4 expression in esophageal cancer; LINC00460 is positively related to ITGA3, LAMC2 expression, and negatively related to FOXO4, KLF15 expression in esophageal cancer (Figure 4E,F). The gene discussed is ITGA3; the disease is esophageal cancer.