In a different cohort of stabilized SLE patients that had been successfully treated with corticosteroid, hydroxychloroquine, and/or immunosuppressants (n = 40) (GSE37356)15, the MMP12 levels were comparable (q = 0.39) to those of healthy controls (n = 32) (Fig. 1c), with no significant differences observed in the levels of IFN-γ response genes IFNGR1 (q = 0.97), IFGNR2 (q = 0.70), ITGAM (q = 0.41), S100A8 (q = 0.27) and S100A9 (q = 0.54), or IFNG (q = 0.50) (Fig. 1c; Supplementary Fig. 2). Here, S100A8 is linked to systemic lupus erythematosus.