Both on admission and on day 2 of hospital stay, serum concentrations of IL-6 correlated with other inflammatory markers (albumin, C-reactive protein, procalcitonin, white blood cells, neutrophils), markers of endothelial dysfunction (sFlt-1, Ang-2), as well as the selected laboratory markers of organ dysfunction (Table 3). The gene discussed is ANGPT2; the disease is endothelial dysfunction.