It was already shown that RSV reduces glutathione (GSH) depletion by augmenting GSH synthesis via activating nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a redox-sensitive transcription factor [52]; RSV also inhibits COPD-related inflammatory mediators, such as IL-6, MCP-1, TNF-α, IL-8, and granulocyte-macrophage colony-stimulating factor (GM-CSF), and decreases nuclear NF-κB expression [53,125,126]. This evidence concerns the gene TNF and chronic obstructive pulmonary disease.