In addition, we tested whether TY-NS-B suppresses cell proliferation and cyclin D1 expression in other cancer cells such as MDA-MB-231 (human breast cancer cell line), AsPC-1 (human pancreatic cancer cell line), A549 (human non-small cell lung cancer cell line) and PC-3 (human prostate cancer cell line). The gene discussed is CCND1; the disease is familial pancreatic carcinoma.