Plasma CHI3L1 was higher in patients with T2D throughout the exercise study (P < 0.05) (Fig. 3D), but otherwise no significant differences in plasma ANGPTL4, muscle expression of ANGPTL4 or CHI3L1, or exercise‐induced changes in expression or plasma levels of ANGPTL4 or CHI3L1 were observed between patients with T2D and weight‐matched controls (Fig. 3A–D). The gene discussed is CHI3L1; the disease is type 2 diabetes mellitus.