However, Chao et al. reported that the predictive sensitivity of NUDT15 p.Arg139Cys for leukopenia was 49.2% in their Chinese IBD cohort, but to determine the diplotype by detecting haplotypes, *5 and *6 could increase the sensitivity to 55.4% [14]. This evidence concerns the gene NUDT15 and Decreased total leukocyte count.