STING1 and infection: STING was activated when infected with herpes simplex virus (HSV) (10, 11), cytomegalovirus (CMV) (12), human immunodeficiency virus (HIV) (13), and Mycobacterium tuberculosis (14, 15) and promoted pathogen elimination; however, STING was triggered by Brucella species (16) and Staphylococcus aureus (17) infection, but facilitated bacterial escape.