EGFR and familial pancreatic carcinoma: Meanwhile, “ErbB signaling pathway” has been reported to be involved in Gemcitabine resistance of pancreatic cancer (Skrypek et al., 2015) and “VEGF signaling pathway” has been reported to be involved in the progression of pancreatic cancer, which may contribute to cell drug resistance (Zhou et al., 2016; Zhu et al., 2016).