The flavonoid, genistein, decreased levels of inflammation mediators, including IL-6, TNF-α by inactivation of NF-κB in alcohol-induced liver fibrosis in rats (Huang et al., 2013; Chen S. R. et al., 2015) and LPS/D-GalN-induced hepatitis in mouse (Lin et al., 2014). Here, TNF is linked to Hepatitis.