We further replicated the methylation differences between MS cases and controls for six out of the seven DMRs using sorted CD14+ monocytes (n = 36, cohort 1), CD19+ B cells (n = 29), as well as CD4+ (n = 33) and CD8+ (n = 29) T cells, with the least pronounced differences being observed in CD8+ T cells (Fig. 4c, Supplementary Data 5). This evidence concerns the gene CD4 and myeloid sarcoma.