Furthermore, the expression levels of KDM1A and HDAC isozymes are correlated, i.e., KDM1A knockdown induces a decrease in the expression of HDAC5 in triple-negative breast cancer [134], while the depletion of HDAC5 leads to the accumulation of H3K4me2 [134]. Here, KDM1A is linked to triple-negative breast carcinoma.