GJB6 and deafness: In their study, the pedigree analysis of such families suggested that many of the additional segregating matings reflect pseudo-dominant transmission in families when one parent with deafness resulting from GJB2 and/or GJB6 mutations married a partner who is deaf for reasons yet to be determined but was also a heterozygous carrier of a single GJB2 or GJB6 mutation.