The secretion of mucous by goblet cells plays a key role in the expulsion of intestinal helminths.33 Expression of the Th2 cytokines IL‐4 and IL‐13 is considered important for the induction of goblet cell hyperplasia during helminth infections.51 In the current study, goblet cell hyperplasia was unaffected in the large intestines of T. muris‐infected CXCR5ΔDC mice, despite the impaired expression of IL‐4 in their MLN. Here, IL13 is linked to helminthiasis.