We have assessed the association of four androgen pathway related genetic polymorphisms (Steroid 5 Alpha-Reductase 2 (SRD5A2) rs632148, Cytochrome P450 Family 17 Subfamily A Member 1 (CYP17A1) rs743572, AKR1C3 rs12529 and Microseminoprotein Beta (MSMB) associated SNP rs10993994) with PC risk and associated factors in a cohort of men from Auckland, NZ [13]. Here, SRD5A2 is linked to pachyonychia congenita.