A previous study has suggested that inhibition of ACh-esterase (AChE) activity may have a positive effect in the treatment of MS (56, 57), and Mazzanti et al. have shown that IFN-β reduces AChE activity in different brain structures from rats experimentally demyelinated by ethidium bromide (58) improving the hypothesis that ACh modulates the inflammatory process (14). The gene discussed is ACHE; the disease is myeloid sarcoma.