LETM1 and fibrosis: PCR array analysis demonstrated that those genes which had their expressions significantly upregulated in WR group are associated with fibrosis (FRS3), vesicle trafficking (SEC24C), cellular viability (LETM1), protection, maintenance and adhesion of lysosomes (LAMP2), neuronal migration and neurite branching and elongation (ULK4), folding and assembly of proteins in the endoplasmic reticulum (HSPA5), and regulation of inflammation (GPSM3).