The subsequent Dunn–Bonferroni test showed that the proportion of CD3+CD8−IL-17A+IFNγ− Th17 cells in MCIAD was significantly elevated compared to controls (z = −0.61231, p = 0.007; dCohen = 1.07) and subjects with MCIother (z = −0.55007, p = 0.019; dCohen = 0.95), indicating that circulating CD3+CD8−IL-17A+IFNγ− Th17 cells are elevated especially in early stages of AD. Here, IFNG is linked to Alzheimer disease.