Similarly, anti-SSA/Ro antibodies have been reported to be strongly associated with low C3 (hypocomplementemia) and clinical phenotypes such as photosensitivity, subacute cutaneous lupus erythematosus, cutaneous vasculitis (palpable purpura), hematological disorder (anemia, leukopenia, and thrombocytopenia) (220–227), as well as Jaccoud’s arthropathy (a type of arthritis) (228, 229). This evidence concerns the gene CALR and hematologic disorder.