NDUFA8 and Parkinson disease: Next we interrogated the KEGG pathway and found the top up-regulated categories showed strong correlation with Alzheimer’s, Huntington’s and Parkinson’s diseases (Fig. 5F) by enriching genes such as ATP5D, ATP5H, HSD17B10 and NDUFB11, NDUFA8, NDUFB7, NDUFS8.