TET2 and pure red-cell aplasia: Rare germline coding variants in TET2 have previously been reported to be enriched in aggressive PrCa cases of African ancestry; however this association was ethnicity specific and was not found for European ancestry individuals.42 Within our cohort, we observed truncating TET2 mutations in 3 patients, all non-aggressive, whilst Tier 2 variants were identified in one additional metastatic and one non-aggressive case.