Alzheimer’s disease (AD) is an age-related neurodegenerative disorder characterized by progressive memory loss [1], intracellular neurofibrillary tangles (NFTs) composed of microtubule-associated protein tau, and extracellular amyloid plaques formed by amyloid-β (Aβ) aggregates in the brain [2]. The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.