MGMT and large cell neuroendocrine carcinoma: In order to elucidate the status of MGMT methylation and 1p/19q co-deletion in PC and LCNEC patients, two cases of AC, seven cases of TC, and six cases of LCNEC patients who underwent surgery were assimilated retrospectively and studied from the Zhejiang Cancer Hospital in China between 2008 and 2016.