Although our results do not argue for a biological effect of monoallelic deletions of MAP3K7 in T-ALL, the fact that T-ALL cells require residual expression of MAP3K7 may imply the potential of MAP3K7 as a new treatment target: If MAP3K7 is not a tumor suppressor but co-deleted with another, yet to be identified tumor suppressor on 6q15, it may behave as a “CYCLOPS” gene [57]. The gene discussed is MAP3K7; the disease is acute lymphoblastic leukemia.