STAT3 and primary effusion lymphoma: Consistently with the evidence that several tumor viruses are associated with STAT3 activation [91,92], Muromoto et al. reported that Kaposi’s sarcoma-associated herpesvirus (KSHV)-encoded latency-associated nuclear antigen (LANA) directly interacts with STAT3 and augments its transcriptional activation in primary effusion lymphoma (PEL) cell lines [45].