The N-BMI-HF group had higher plasma insulin (p ≤ 0.05), leptin (p ≤ 0.01) and Hs-CRP (p ≤ 0.05) concentrations and higher HOMA-IR values (p ≤ 0.05), when compared to those of the N-BMI-NF adolescents. This evidence concerns the gene INS and hydrops fetalis.