Although the mechanisms concerning the functional role of LRP1 in efferocytosis in atherosclerosis are still not fully understood, it has been found that LRP1 integrates a multiprotein complex (composed of the receptor tyrosine kinase AXL and RAN-binding protein 9 RANBP9) which mediates dendritic cell (DC) efferocytosis and antigen cross-presentation [69]. The gene discussed is RANBP9; the disease is atherosclerosis.