Interestingly, expression levels of genes involved in ripoptosome signaling, such as RIPK3 and MLKL, were also comparatively increased in mesenchymal GBM subtype, and their values correlated to TLR2 (r = 0.795 and r = 0.661, respectively), and to TLR4 (r = 0.575 and r = 0.360, respectively). Here, TLR4 is linked to glioblastoma.