ACE and alcohol dependence: Literature Lab, based on 106,967 abstracts for “Drinking” Physiology from MeSH (Medical Subject Headings), identified enrichment (P < 0.00001) related to ALDH2 (known to be associated with alcohol dependence)[15] and several other genes, including our novel finding for ERCC6, CATSPER2, GABRB1 and GATA4. The main contributor for “Angiotensin II” (P < 0.00001) was AGT and ACE for “Hypertension” (P = 0.0002).