MGMT and neoplasm: Detailed individual patient data of the ADCTA and reference groups including sex, age, extent of tumor resection, receiving TMZ or not, receiving radiation therapy/CCRT or not, receiving salvage gamma knife (GKS) for recurrent/residual tumor or not, Karnofsky performance score (KPS), and survival and recurrence (shown as OS and PFS in months), together with tumor expression of IDH1, MGMT, and PD-L1; PD-1+, CD4+, and CD8+ lymphocyte counts; and PD-1+/CD8+ ratio in lymphocytes are shown in Tables 2 and 3.