We utilized oral glucose tolerance tests (OGTT) to categorize youth as having normal glucose tolerance (NGT), or dysglycemia [OGTT values consistent with prediabetes defined as impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT), and T2D], and (b) to examine the associations between OGTT-derived measures of glucose tolerance, insulin sensitivity, and insulin secretion and PSG-derived measures of OSA. The gene discussed is INS; the disease is type 2 diabetes mellitus.