To confirm the clinical relevance of these experimental results, we analyzed FN1 expression in 114 tissues of early node-negative NSCLC patients (patient characteristics are reported in Supplementary Table 2), in parallel with Pan-hMENA and hMENA11a staining, scored as hybMENA11a-positive (which denotes cases with hMENA11a high/hMENA(t) low) or -negative (all other cases including tumors expressing hMENAΔv6) [10]. Here, FN1 is linked to non-small cell lung carcinoma.