BCSCs (CD24− CD44+ ESA+) isolated from MCF10DCIS.com cells, which give rise to ductal carcinoma in situ, exhibit higher expression levels of lipogenic genes such as ATP citrate lyase (ACLY), acetyl CoA carboxylase 1 (ACC1), and FASN compared to non-stem cancer cells(Fig. 1). Here, ACLY is linked to cancer.