TYROBP and Alzheimer disease: TREM2 and other late-onset AD susceptibility genes MS4A4A/4 E/6A, CD33, HLA-DRB5/DRB1, and INPP5D are all part of a distinctive brain coexpression module, which also contains the signaling partner for TREM2, TYROBP, or DAP12 (Forabosco et al., 2013, Hawrylycz et al., 2012, Zhang et al., 2013).