LILRB1 and Iron deficiency anemia: To further address this issue and to directly determine whether LIR1 had an impact on the iron-deficiency phenotype of irt1-/- A. thaliana, we generated transgenic irt1-/- plant lines expressing LIR1. These transgenic plants presented a markedly worsened chlorotic phenotype and had a more severe growth defect, when compared to the irt1-/- line not expressing LIR1 (Fig 3c, top panels).