This thought is especially tantalizing, as it was shown that the related Trypanosoma brucei, which may also confer myocardial disease, can directly induce CaMKII-mediated proarrhythmogenic SR calcium leak in cardiomyocytes [17] and an upregulation of the chemokines CCL2 and CCL3 was found in T. cruzi-associated cardiomyopathy [53], which, we know now, is driven by CaMKII [105]. This evidence concerns the gene CAMK2G and myocardial disorder.