More typically, hypouricemia is associated with high fractional excretion of uric acid due to genetic causes; including mutations in genes such as SLC22A12 (URAT1) (39, 127) and SLC2A9 (GLUT9) (62, 84) or factors such as uricosuric usage, renal tubulopathy, neoplasias, and other conditions (124, 127). Here, SLC22A12 is linked to neoplasm.