In terms of translational value, it is exciting to report that when 7DW8-5 and an adenovirus-based human malaria vaccine were co-administered to our cutting-edge humanized mice that possess functional human CD8+ T cells andiNKT cells37, 7DW8-5 was shown to enhance not only the malaria antigen-specific human CD8+ T-cell response but also the efficacy of the vaccine37. The gene discussed is CD8A; the disease is malaria.