Nevertheless, primary uterine leiomyosarcoma showed high RORβ expression (30), pharyngeal carcinoma cells and colorectal cancer cells showed modulated RORβ expression (29, 31), and RORβ was related to metastasis in a metastatic colorectal cancer cell model (28), which are summarized in Table 1. This evidence concerns the gene RORB and colorectal cancer.