MYO6 (myosin VI, MIM*600970) is involved in autosomal dominant deafness type 22 (DFNA22) due to both missense and truncating mutations [19] and thus might explain the deafness seen in 5/23 individuals with a deletion including MYO6. However, in DFNA22, deafness is progressive with an age of onset of 20 years and onwards, while the individuals with hearing problems in our cohort range in age from 8 months to 22 years, with an unknown age of onset of their hearing loss. Here, MYO6 is linked to deafness.