ALKBH5 and non-small cell lung carcinoma: To identify the post-transcriptional or epitranscriptional regulators modulating UBE2C in NSCLC, we first examined the specific post-transcriptional regulators miR-381 and ALKBH5 for UBE2C in NSCLC, in which miR-381 represses UBE2C via targeting its 3′UTR and ALKBH5, one of de novo m6A demethylase, stabilizes the UBE2C transcripts by reducing the m6A methylation level inside its mRNAs.