Taken the IHC results together, in HNSCC the NTRK1 staining was high in the majority of the tumor cell nests, the tumor cells were either stained for NTRK1 or for p75NTR, in the case if both receptors were present, the cells stained with p75NTR and the ones stained with NTRK1 were mutually exclusive. The gene discussed is NTRK1; the disease is head and neck squamous cell carcinoma.