In addition, overexpression of CBX3 increased the movement of KP3L and PANC-1 cells towards the wound center in wound healing assay (Figure 2f), as well as promoted their invasion through extracellular matrix (Figure 2g), suggesting that CBX3 overexpression can result in increasing aggressiveness of PAAD cells. This evidence concerns the gene CBX3 and pancreatic adenocarcinoma.