CD40LG and diabetes mellitus: In contrast, the diabetes group had a significant higher IgM antibody (Fig 4A) compared to the non-diabetes group (median OD 0.24, IQR 0.18–0.48 versus median OD 0.22, IQR 0.13–0.33, P = 0.032) while there was no difference of IgG antibody levels between the diabetes and non-diabetes group of melioidosis patients (median OD 0.66, IQR 0.28–1.74 versus median OD 0.46, IQR 0.20–1.02, P = 0.063) (Fig 4D).