As ART eligibility increased from a required CD4 count <350/μL to Test and Start, the percentage of all clients initiated on ART increased from 66% to 96%, the percentage of clients initiated on ART who received same day ART increased from 62% to 87%, and, among 361 clients with newly diagnosed HIV infection, the median CD4 count at ART initiation increased from 313/μL (IQR = 203/μL–422/μL) to 454/μL (IQR = 264/μL–598/μL). This evidence concerns the gene CD4 and HIV infectious disease.