This is important given that Vegfa is expressed in vECs and neural cells in the fetal human brain (Virgintino et al. 2003), and because Vegfa polymorphisms and its downregulation have been implicated in schizophrenia and other mood disorders (Fulzele and Pillai 2009; Gao et al. 2015). This evidence concerns the gene VEGFA and schizophrenia.