VEGFA and lung carcinoma: Vascular endothelial growth factor-positive patients may benefit more from bevacizumab treatment.[24] Previous studies have shown that the time interval between diagnosis of the primary tumor and manifestation of gastrointestinal metastasis ranged between 2 week and 4 years and the mean time between the identification of the gastrointestinal metastasis and mortality was 100.6 days.[18,25] Because of the poor survival of the majority of patients, the early diagnosis and the development of novel systemic therapies for gastrointestinal metastasis of lung cancer are of paramount importance.